Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development
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چکیده
منابع مشابه
Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development
We studied the expression of the estrogen-related receptor 1 (ERR-1) during mouse embryonic development. ERR-1 is expressed at very early stages in ES cells and at E8.5 in the mesodermal cells of the visceral yolk sac. ERR-1 continues to be expressed later in mesodermal tissues and particularly in heart and in skeletal muscles. This expression persists during all the embryonic development and i...
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Estrogen-related receptor (ERR ) is one of the first orphan nuclear receptors to be identified, yet its physiological functions are still unclear. We show here that ERR is an effector of the transcriptional coactivator PGC-1 [peroxisome proliferator-activated receptor (PPAR ) coactivator 1 ], and that it regulates the expression of genes involved in oxidative phosphorylation and mitochondrial b...
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The ERR's (estrogen receptor-related receptors) are constitutive activators of the classical estrogen response element. In this report, we demonstrate that ERRgamma is highly expressed in the nervous system of the developing mouse embryo and that the adult pattern of expression of ERRgamma is, with few exceptions, established during embryogenesis. Transcripts are preferentially detected in alre...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 1997
ISSN: 0925-4773
DOI: 10.1016/s0925-4773(97)00059-2